HORDB

ID: hor000913
Uniprot ID: A0A060YTT7(99-119)
Protein name: CCK-21
Gene name: ccka
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Family: Gastrin/cholecystokinin family
Source: animal
Expression: pyloric caeca
Disease: NA
Comments: NA
Taxonomy: Oncorhynchus (genus), Salmoninae (subfamily), Salmonidae (family), Salmoniformes (order), Protacanthopterygii, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction; GO:0007586 digestion
GO CC: GO:0005576 extracellular region

Sequence: ASGPGPSHKIKDRDYLGWMDF
Length: 21(99-119)
Propeptide: MNAGICVCVLLAAFSGSSLGRPSHSQDEDKPEPPQLDSVMSPQHTRHTRSAPSSGQLIPFSKPAEDEAEDPRTSLRELLARLISRKGSLQRSSSLSSRASGPGPSHKIKDRDYLGWMDFGRRSAEEYEEYSS
Signal peptide: MNAGICVCVLLAAFSGSSLG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000913_AF2.pdb

hor000913_ESM.pdb

Mass:	273458	Formula:	C107H157N29O31S
Absent amino acids:	CENQTV	Common amino acids:	DG
pI:	7.54	Basic residues:	4
Polar residues:	6	Hydrophobic residues:	5
Hydrophobicity:	-92.38	Boman Index:	-4165
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	41.9
Instability Index:	3185.71	Extinction Coefficient cystines:	6990
Absorbance 280nm:	349.5

PubMed ID: 11342099
Title: Identification and Distribution of CCK-related Peptides and mRNAs in the Rainbow Trout, Oncorhynchus Mykiss